The existence of different genetic forms of ALS makes itpossible to design representative cellular and animal models of the diseasebased on the expression of mutations in the genes SOD1,TARDBP, FUS, etc. in model organisms;transgenic B6SJL-Tg (SOD1–G93A) mice are the most commonly used animalsin these experiments [3]. Here, TARDBP is linked to amyotrophic lateral sclerosis.