RAI treatment, radioactive 131 iodine therapy; BMI, Body Mass Index; TAO, thyroid-associated ophthalmopathy; ATD, Antithyroid drugs; TSH, thyroid stimulating hormone; TRAbs, serum anti-TSH receptor autoantibodies; T3, Triiodothyronine; T4, Tetraiodothyronine; FT3, free triiodothyronine; FT4, free thyroxine; RAIU, Radioactive iodine uptake. The gene discussed is TSHR; the disease is thromboangiitis obliterans.