Another single cell study [167] comparing the snRNA-Seq profiles of COVID-19-infected AD patients and COVID-19-infected cognitively normal individuals found that two SARS-CoV-2 docking receptors, NRP1 and BSG, had elevated expression in endothelial cells in the prefrontal cortex of both AD patients and healthy controls compared to other brain cell types. This evidence concerns the gene BSG and Alzheimer disease.