FLT3 and acute myeloid leukemia: The results obtained with CP-456773 (Fig. 2h) were validated, as the combination treatments with CY-09 or Disulfiram and FLT3 inhibitors (Fig. 2j + k) produced similarly strong pro-apoptotic effects in FLT3-ITD mutant AML cell lines, despite being used at significantly lower concentrations.