ERBB2 and breast cancer: 2-deoxy-2-[18F]fluoro-D-glucose ([18F]FDG) Positron Emission Tomography / Computed Tomography (PET/CT) has been investigated in the last 10 years for imaging BC patients and recently included into guidelines also for the assessment of response to NAC in TNBC and human epidermal growth factor receptor 2 (HER-2) enriched BC [11–13].