SPAAR and breast cancer: To study the potential impacts of LINC00961 and hSPAR on breast cancer, we built three hSPAR mutant constructs fused with C-terminal Flag tags (ΔATG1, ΔATG2, and ΔATG1 + 2) by mutating the ATG codon(s) to ATT on ORF1 or/and ORF2 (Fig. EV1C).