Upon analyzing The Cancer Genome Atlas (TCGA) database, we found that the expression level of LINC00961 was significantly downregulated in breast invasive carcinoma (BRCA) (Fig. 1A), with similar patterns in all 4 listed subtypes (triple-negative, HER2 + , Luminal-A, and Luminal-B) (Fig. 1B). This evidence concerns the gene SPAAR and invasive breast carcinoma.