By exploring the DepMap database and combining gene expression data from the Cancer Cell Line Encyclopedia (CCLE) [42], we found that the mRNA level of VISTA in CRC cells was comparable to the mRNA level in ovarian cancer and melanoma cells, which was recently reported to be associated with VISTA expression [26, 27] (Supplementary Fig. S6A). The gene discussed is VSIR; the disease is colorectal carcinoma.