Here, we provide a potential mechanism through which Blautia and Lachnoclostridium spp., alongside many other commensal species, are able to metabolize the oxidized sugars produced in the inflamed gut as orthogonal carbon sources and demonstrate that the gud/gar genes providing this functionality are increased in abundance and transcription in IBD patients compared to non-IBD controls. Here, WT1 is linked to inflammatory bowel disease.