CD274 and cancer: The analysis of the KEGG pathways of 610 mRNAs in the negatively correlated network of miRNA-mRNA revealed that the genes associated with this network were enriched mainly with Viral protein interaction with cytokine and cytokine receptor Proteoglycans in cancer and Cell adhesion molecules, Cytokine-cytokine receptor interaction, Chemokine signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Rap1 signaling pathway, T cell receptor signaling pathway, Pathways in cancer, JAK-STAT signaling pathway.