ADAMTS5 and neoplasm: Conversely, TQ treatment resulted in the downregulation of several genes overexpressed in GBM cells, including potential oncogenes like AEBP1, MIAT, GHR, LMO1, ELF3 [60–64], and genes involved in tumor proliferation and migration such as EPHA4, COL3A1, PCDH10, ROBO1, ADAMTS5, PCDH18, ST8SIA1 [65–70].