FTO mediated m6A demethylation of glutamine transporter SLC1A5 and autophagy regulators ATG5 and ATG7 stabilizes and destabilizes respectively, their mRNA transcripts through the action of m6A readers, thereby promoting ccRCC by increasing glutamine uptake and inhibiting autophagy [66,67]. The gene discussed is SLC1A5; the disease is nonpapillary renal cell carcinoma.