For instance, lung NETs with high DLL3 expression harbored statistically increased proportions of B cells (7.21% vs. 6.04%; q = 0.032), dendritic cells (7.97% vs. 5.11%; q = 0.002), and M1 macrophages (1.80% vs. 1.03%; q = 0.009), with a relative depletion in M2 macrophages compared with DLL3-low lung NETs (2.64% vs. 4.41%; q = 0.003). This evidence concerns the gene DLL3 and medical procedure.