There is currently no research into the mechanism of eosinophilia in specifically CD30 + LPD; however, similar to other entities discussed in this article, it likely involves the secretion of pro-eosinophilic cytokines by bystander Th2 T-cells and potentially by the neoplastic cells. Here, TNFRSF8 is linked to disseminated peritoneal leiomyomatosis.