Further, we found that anti‐tumour H‐2Kb‐SIINFEKL+ CD8+ T cells were increased by two‐ to three‐fold in the blood of ACM‐OVA + free CpG‐immunised mice on day 21 p.i., as compared to the other two groups (Figures 3J and S4). This evidence concerns the gene CD8A and neoplasm.