The 12 shared DEGs including HSPB1, VIM, MVD, TUBB4A, AACS, ANXA6, DIRAS2, RPH3A, CEND1, KALM, THOP1, AREL1, previous studies have shown that these DEGs are highly correlated with nHIBD and AD. Here, DIRAS2 is linked to Alzheimer disease.