miR-21a-5p improved hyperlipidemia via the inhibition of its targets FABP7, 3-hydroxy-3-methylglutaryl CoA reductase (HMGCR), acetyl CoA acetyltransferase 1 (ACAT1), and oxidized low-density lipoprotein receptor 1 (OLR1) [21]. This evidence concerns the gene ACAT1 and hyperlipidemia.