NT5E and neoplasm: CD73 further converts extracellular AMP into adenosine, which is known to balance inflammatory processes in normal tissues and to promote immune escape in the tumor microenvironment (Yang et al., 2021; Han et al., 2022; Bach et al., 2023; Kaur and Dora, 2023; Kowash and Akbay, 2023; Stagg et al., 2023).