IL2 and neoplasm: Eight days post-NIR exposure, the average tumor volume in the THT plus i.t. IL-2 group [120.7 mm3 (± 29.6 mm3)] was significantly lower compared to 235.7 mm3 (± 111.1 mm3) in the control group, 281.6 mm3 (± 150.5 mm3) in the i.t. IL-2 only group, and 271.5 mm3 (± 169.8 mm3) in the THT only group (Figure 5C).