As the main component of myelin, PLLP promotes myelin formation by inducing myelin precursor domains in the Golgi apparatus after phosphorylation (38).Based on our findings, we speculate that the reason why the decreased expression of PLLP can promote the development of SCLC might be related to the neuroendocrine characteristics of SCLC. This evidence concerns the gene PLLP and small cell lung carcinoma.