GLUD1 and glioblastoma: For example, the transcription factor pleomorphic adenoma gene 1 (PLAG1) controls GDH1 expression during anoikis resistance [43], the protein but not mRNA level of GDH1 is induced when proliferating mammary epithelial cells undergo quiescence [45], and GDH1 enzymatic activity but not the protein level is elevated when glucose oxidation is inhibited in glioblastoma cells [44].