To corroborate this finding, we also extracted TMEM106B fibrils from two other brain tissues, one from case 2 of PDD patient and the other from case 6 of non-neurodegenerative disease (non-ND) control (Table 1), corresponding to PDD case and normal 2 case in our previously study [34], respectively. The gene discussed is TMEM106B; the disease is neurodegenerative disease.