TGFB1 and renal fibrosis: Although Fer-1 didn’t affect the decline of cell viability induced by TGF-β (Figure 3B), which has been confirmed in a reported literature (Kim et al., 2021), Fer-1 still exerts marked effects on attenuating ferroptosis in vivo and in vitro, which further corroborates that ferroptosis serves as a critical role during renal fibrosis.