IGF1 and infection: It is a product derived from autologous blood through the process of centrifugation; it contains high platelet concentration as well as many growth factors, some of which include platelet-derived growth factor, IGF, FGF, and TGF, among others.6, 8As PRP aids in wound healing and has immunological property that help in rapid wound healing with reduced scarring and infections, combining it with myringoplasty provides a better surgical success rate.