Stx3 accumulates in the outer segment in models of retinal degeneration caused by defects in the BBSome (Datta et al., 2015; Dilan et al., 2018; Hsu et al., 2017), but not in Ift20 and Ift172 knockouts (Lewis et al., 2024). This evidence concerns the gene IFT172 and retinal degeneration.