TNF and type 2 diabetes mellitus: Accordingly, a study among 2363 patients with prediabetes and type 2 diabetes demonstrated that sedentary behavior was linked to increased low‐grade inflammation biomarkers (i.e., C‐reactive protein, soluble intercellular adhesion molecule‐1, IL‐6, and TNF‐α), as well as endothelial dysfunction biomarkers [38].