In addition, the Case presented lower frequencies of the B trans cluster (B transitional cells, CD38++ CD27+IgD+ CD20+ CXCR5+ CD45RA+ CD25+) and lower frequencies of pDC cluster (plasmacytoid Dendritic Cells, CD11c− CD123+) and ILC-like cells (Innate Lymphoid Cells, CD45low CD3− CD19− CD25highCD127+ CD161+ CD45RA+ CD11c−), mirroring SLE patients compared to HCs. This evidence concerns the gene CXCR5 and systemic lupus erythematosus.