In spite of this, after etoposide incubation only SLE granulocytes exhibit induced levels of γ-H2AX, while DNA-damage levels fall to levels equal to healthy control in AGS patient (Fig. 5C). This result might be explained by increased apoptosis levels of PBMCs in AGS Case, as described previously. The gene discussed is H2AX; the disease is systemic lupus erythematosus.