AKT1 and neoplasm: DEGs were mainly enriched in pathways related to cell death, the immune response, and tumor signal transduction, such as protein ubiquitination (Ub), protein phosphorylation, TOR signaling pathway, phosphoinositide 3-kinase (PI3K)-Akt signaling pathway, and T cell receptor signaling pathway (Fig. 4b, Additional file 1: Fig. S7a).