Interestingly, FMN is proved to have anti-apoptotic and anti-inflammatory properties through suppression of the NLRP3 inflammasome in mice with autoimmune hepatitis (Liu et al. 2021b). Wu et al. (Wu et al. 2018) have demonstrated that FMN treatment can ameliorate dextran sulfate sodium-induced acute colitis through repressing the NLRP3 inflammasome. Here, NLRP3 is linked to autoimmune hepatitis.