Regarding day 8 tumor infiltration, a larger decrease in peripheral lymphocyte count on day 1 correlated with less NK cells and CD8+T cells in filtrating into tumors (p=0.0298 and p=0.0077, online supplemental figure 2B), but interestingly smaller rebound of the lymphocyte count from day 1 post-treatment to day 8 pretreatment levels correlated with more CD8+T cells infiltrating the tumors (p=0.0172, online supplemental figure 2C). Here, CD8A is linked to neoplasm.