Analysis of data from The Cancer Genome Atlas (TCGA) and the Clinical Proteomic Tumor Analysis Consortium (CPTAC) shows that many tumors retain or increase the expression of 4E-BP1 mRNA (Supplemental Figure 1; supplemental material available online with this article; https://doi.org/10.1172/JCI176093DS1) and protein (Figure 1A, arrowheads). The gene discussed is EIF4EBP1; the disease is neoplasm.