P2RX7 and type 2 diabetes mellitus: Three P2X7 SNPs (rs7958311, OR = 1.448, p<0.001; rs208294, OR = 1.315, p = 0.005; rs11065464, OR = 0.734, p = 0.002) were found to be associated with T2DM risk, while the other SNPs showed no significant association with T2DM susceptibility.