Whole exome sequencing (WES) data were analyzed to assess all coding regions of the aforementioned genes, including both single nucleotide variants and copy number variations in CFTR, SBDS, EFL1, eIF6, DNAJC21, SRP54, UBR1, COX4I2, PDX1, PTF1A, GATA6, and PNLIP. This analysis evaluated all CFTR variants, ultimately excluding a diagnosis of CF. This evidence concerns the gene CFTR and cystic fibrosis.