OGT and neoplasm: Furthermore, 4T1 cells harboring the YAP T83A mutation, which impairs YAP O‐GlcNAcylation, also exhibited a pronounced inhibitory effect on tumor metastasis (Figure S9H, Supporting Information), suggesting that the HBP‐OGT‐EIF3H‐YAP axis contributes to TNBC metastasis and highlighting the potential of targeting this pathway to suppress metastatic progression.