YAP1 and neoplasm: To specifically investigate the role of YAP O‐GlcNAcylation in promoting tumor growth in vivo in obese mice, we injected HFD‐fed obese mice with either 4T1 cells (BALB/c mice) (Figure 7D,E) or MDA‐MB‐231 cells (nude mice) (Figure S9C,D, Supporting Information) and treated them with a 5 mg kg−1 OGT inhibitor twice weekly.