Moreover, SLC7A11 was reported to be related to PI3K/AKT/mTOR signaling pathway in cancers, such as gastric cancer (17), glioma (18), pancreatic carcinoma (19), neuroendocrine tumors (20), but the interaction has not been clarified in breast cancer. This evidence concerns the gene SLC7A11 and exocrine pancreatic carcinoma.