While infection led to an expansion of LTHSCs, the numbers of LTHSC, granulocyte progenitors (GP), and other progenitors (including common lymphocyte progenitors (CLPs), common myeloid progenitors (CMPs), and granulocyte monocyte progenitors (GMPs)) (data not shown) were not impacted by the absence of IL-27 (Fig. 1E). This evidence concerns the gene IL27 and infection.