We were not able to observe a significant difference in cytokine secretion between IFN-γ-treated monocytes from healthy donors and ROSAH disease patients (Figure 1H), possibly due to the large interindividual variability in cytokine secretion, to the low number of ROSAH patients included in this study and to the fact that some of these patients were under treatment. Here, IFNG is linked to retinal dystrophy, optic nerve edema, splenomegaly, anhidrosis, and migraine headache syndrome.