Given the critical role of inflammatory cytokines, such as TNFα, in the progression of both ERU (13, 57, 58) and human recurrent uveitis (59–61), we next evaluated the ability of the SOCS1-KIR mimetic to regulate cytokine production in activated equine PBMCs (untreated controls were provided here for baseline reference). The gene discussed is SOCS1; the disease is uveitis.