Dates fruit is very rich in trace elements, polyphenols, and phytochemicals, the fruit and due to its antioxidant capacity and effects on tumor necrosis factor expression; had the potential to mitigate DNA damage.18 Therefore, dates fruit is suitable for patients with diabetes due to the high prevalence of malnutrition observed among them.19 In addition, animal studies showed that date extracts are beneficial in dyslipidemia (lower low-density lipoproteins, total cholesterol, and triglycerides, and higher high-density lipoproteins).20,12. This evidence concerns the gene TNF and diabetes mellitus.