MKI67 and breast cancer: The proper assessment of axilla status is crucial and in presence of high risk features including large tumor size, high Ki-67 (proliferative index) and high grade disease further assessment may be required for exclusion of probability of nodal metastasis which carry higher risks of nodal involvement.22 With high sensitivity in diagnosing axillary metastasis, US is a non-invasive modality and can predict nodal positivity in breast cancer patients.