PGK1 and breast cancer: In parallel, a novel prognostic risk signature for breast cancer patients was constructed using 11 cuproptosis hub genes namely, PGK1, MRPL39, COPB2, HSPH1, NFKBIA, PRDX1, PCMT1, MPZL3, DLG3, DIP2B, LACTB2 (Shen L. et al., 2022).