Compared with the lowest quartile (Q1) group, individuals in the highest METS-VF group (Q4) were more inclined to be aged 40–65 years, males, Non-Hispanic White, above high school level, married, PIR ≥3.5, former smokers, those who never consumed alcohol, hypertension, diabetes, hyperlipidemia, CKD, CVD, low physical activity, more individuals using diuretics, and higher AST and ALT. This evidence concerns the gene GPT and hyperlipidemia.