Diabetes mellitus or glucoseor insulin or hyperglycaemiaor prediabetes cholesterol or triglycerides or bloodpressure or metabolicsyndrome or hypertension or hyperlipidaemia or lipoprotein or HbA1c or cardiometabolic or waist circumference orbody mass index or BMI or hypercholesterolemia orhypertriglyceridemia or high density lipoprotein or low density lipoprotein. The gene discussed is INS; the disease is Hypertension.