PTPRR and brain neoplasm: The most common type of pineal gland tumors is germ cell tumors, followed by pineal parenchymal tumors that include pineocytoma (World Health Organization (WHO) grade 1), pineal parenchymal tumors of intermediate differentiation (WHO grade 2-3), PTPR (WHO grade 2-3), and pineoblastoma (WHO grade 4) [2,3]. PTPR was recognized as a distinct entity by the WHO in 2007 [4]. There is no established staging system. Less than 8% of pineal gland tumors are PTPR, under 0.08% of all primary brain tumors, making it very rare [5].