A total of 41 novel variants were identified in PD genes, including four in GBA1, seven in PINK1, two in DNAJC6, four in DJ-1, one in SNCA, five in PRKN, three in LRRK2, twelve in VPS13C, two in VPS35, and one in SYNJ1 (Supplementary Table 2, Figure 4). The gene discussed is PINK1; the disease is Parkinson disease.