We focused on known PD-associated genes linked to autosomal dominant inheritance (SNCA, LRRK2 and VPS35), autosomal recessive inheritance (PRKN, PINK1, DJ-1, and VPS13C), and increased risk (LRRK2, GBA1), as well as other PD-associated genes such as RAB32, PSMF1, and ITSN1 from literature. The gene discussed is VPS35; the disease is Parkinson disease.