A total of 41 novel variants were identified in PD genes, including four in GBA1, seven in PINK1, two in DNAJC6, four in DJ-1, one in SNCA, five in PRKN, three in LRRK2, twelve in VPS13C, two in VPS35, and one in SYNJ1 (Supplementary Table 2, Figure 4). This evidence concerns the gene PRKN and Parkinson disease.