Stratified by AARC score, the IL-6 levels were significantly elevated in the ACLF+COVID-19 patients with an AARC score grade I (80.12 [81.29-82.45] vs 11.15 [13.22-15.28]; p=0.018) and II (230.44 [81.87-495.25] vs 36.84 [12.85-81.01]; p=0.001) compared with the ACLF group. The gene discussed is IL6; the disease is COVID-19.