Fig. 4 shows the effects of CAD on the differentendpoint events for the different subgroups CAD was not significantly associatedwith all-cause mortality, cardiovascular death, or SCD in subgroups stratified bygender, age, New York Heart Association functional class, syncope, AF, leftventricular diameter, LVEF, or NT-proBNP in the matched cohort. This evidence concerns the gene NPPB and Schnyder corneal dystrophy.