Pseudo-Meigs syndrome is characterized by hydrothorax and ascites associated with pelvic masses; the patients occasionally present with elevated serum CA-125 levels. The syndrome-related tumors are conditions other than those observed in Meigs syndrome; they include ovarian malignancies (primary or metastatic ovarian tumors), ovarian struma ovarii, uterine cancers, uterine hemangioma, uterine leiomyoma, and yolk sac tumors. Here, MUC16 is linked to yolk sac tumor.