The risk factors associated with this uncommon form of glomerular injury in kidney allografts include, but are not limited to, the donor's high-risk APOL1 genotype, viral infections (such as cytomegalovirus, human immunodeficiency virus, Epstein-Barr virus, SARS-CoV-2, parvovirus, and BK virus). The gene discussed is APOL1; the disease is viral infectious disease.