In another study conducted by Fernandez-Morera et al. (2008) the MICB*004 allele frequency was significantly increased in patients with MS (46.3 vs. 23.3%, Pc < 0.001, odds ratio 2.82, 95% confidence interval 68–4.73), and only the frequency of the HLA-DRB1*01 allele was increased in controls (31 vs. 14%, Pc = 0.011). This evidence concerns the gene MICB and myeloid sarcoma.