Contrary to this observation, monoclonal anti-Gp70 antibodies were capable of controlling experimental sporotrichosis caused by S. brasiliensis, and Gp70 peptides were found as good candidates to develop a CD4+-dependent protective immune response against subcutaneous sporotrichosis (de Almeida et al., 2015; de Almeida et al., 2017; de Almeida et al., 2018). The gene discussed is CD4; the disease is sporotrichosis.